NHS DigiTrials

Clinical trials enable the development of new and improved treatments to transform patient lives. As important as these trials are for improving patient care, they can be difficult to establish and run.

NHS Digital saw a valuable opportunity to support clinical trials while protecting patient privacy with the scale and reach of the data held in trust for the nation.

Working in partnership with the University of Oxford Big Data Institute, IBM and Microsoft, and commissioned by Health Data Research UK through the UK Research and Innovation Industrial Strategy Challenge Fund, we have created the NHS DigiTrials Service to provide data, expertise and infrastructure specific for clinical trials.

The first release of the service focuses on enabling a rapid feasibility assessment of the number and location of eligible patients through secure analysis of clinical and demographic data sets.

This service aims to:

• enable more opportunities for participation in research
• reduce the cost and complexity of developing new treatments
• reduce drug costs to the NHS improve the quality of evidence on the effectiveness and safety of new treatments for patients and their doctors. 

We have worked closely with clinical trialists and patients to ensure they have been included in the design of this service. 

Further phases are subject to funding include:

• Identification: Identifying suitable patients to be invited by the appropriate investigator to participate in a clinical trial
• Communication: Improving communications between clinical trialists, patients and their general practitioners before, during and after the trial
• Outcomes:  Linking trial cohorts to NHS data sources to collect information on relevant medical events to provide an efficient and comprehensive assessment of clinical safety.

The feasibility service will support searches across:

• Personal Demographics Service (PDS) 
• Hospital Episode Statistics (HES)
• Civil Registration of Deaths (ONS)

We will update this list as additional data sets are made available. If you have any specific data sets you think would be beneficial to be added to this service please email us.

We are developing a range of analyses which we hope will encourage patients to participate in trials in the future including the number and location of patients who meet certain demographic clinical eligibility criteria or for patients who may be based near a research trial site.

All outputs (data) from the service are anonymous and provided as tables with small numbers suppressed to protect individual privacy. These can also be supported by maps.   

This is a chargeable service. Learn more about DARS charging information. 

Recognising that clinical trials will be focused on Covid-19 for the foreseeable future, and understanding the need for outcome data to support this vital work - namely data about clinical interventions across a range of care settings - we have taken the decision to move beyond a core feasibility offer. 

We will continue to make incremental improvements to supporting feasibility, but are pivoting resource to support the large number of requests for outcome data that we are now receiving. 

Focusing on outcomes data will better address current clinical trial needs and is central to our vision of creating a service that provides clear benefits at the right time and in the right way. 

Improving health and care relies on better pathways and treatments. These are validated by carefully controlled clinical trials.

NHS Digital aims to support researchers to make the best use of the data we hold in trust to select the most appropriate participants. This not only reduces the cost of the trial but should also improve the quality of the study leading to better pathways and treatments the future.

All of the above services protect individuals’ data rights and only take place where there is an appropriate legal framework in place.

Find out how NHS Digital make sure patient data is protected and handled securely. 

NHS DigiTrials is overseen by a board which has monthly/regular meetings. Learn more about the DigiTrials board.