This document is an event-by-event definition of the events captured by the NDRS Cancer Pathway Dataset. Each event is labelled, numbered, and its properties listed. The methodology used to define the event is given, any data quality /completeness issues are described, and any extra notes for interpretation are also provided.

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Field or property Description
Event name CWT referral
Event number 501
Date updated 12/05/2025
Linkage Tumour
Event definition As recorded by the Cancer Waiting Times (CWT) system, the event of the patient being referred to secondary care, leading to this tumour diagnosis.
Property 1 definition The REF_SOURCE field from the CWT data table
Property 2 definition The PRIORITY_TYPE field from the CWT data table.
Property 3 definition The REF_TYPE field from the CWT data table.
Date definition Where the CRTP_DATE from the CWT table is not missing this is used. If it is missing and the DEC_TO_REF_DATE field is present then that date is used.
Trust definition The TRUST_FIRST_SEEN field in the CWT table is used.
Data source The CWT data table is CASREF02.CWTPROC.TREATMENTS. The linkage table is lnk_tums_cwttrts.
Further methodology Where both DEC_TO_REF_DATE and CRTP_DATE are missing the event is not populated, even if a CWT record exists. This field holds tumour-linked data, using the tumour linkage table specified in the data source.
DQ/Completeness Issues Approximately 25% of cancer patients do not have a CWT record associated with their tumour.
Notes for interpretation Also see event 601, which is partially populated from this field

Field or property Description
Event name CWT First seen
Event number 502
Date updated 12/05/2025
Linkage Tumour
Event definition As recorded by the Cancer Waiting Times (CWT) system, the event of the patient being first seen in secondary care, leading to this tumour diagnosis.
Property 1 definition The REF_SOURCE field from the CWT data table
Property 2 definition N/A
Property 3 definition N/A
Date definition The DATE_FIRST_SEEN field as recorded in the CWT dataset.
Trust definition The TRUST_FIRST_SEEN field in the CWT table is used.
Data source The CWT data table is CASREF02.CWTPROC.TREATMENTS. The linkage table is lnk_tums_cwttrts.
Further methodology Where the DATE_FIRST_SEEN is missing the event is not populated, even if a CWT record exists. This field holds tumour-linked data, using the tumour linkage table specified in the data source.
DQ/Completeness Issues Approximately 25% of cancer patients do not have a CWT record associated with their tumour.
Notes for interpretation Also see event 602, which is partially populated from this field

Field or property Description
Event name Radiology
Event number 503
Date updated 12/05/2025
Linkage Patient
Event definition A radiology event, as recorded in the Diagnostic Imaging Dataset (DID).
Property 1 definition Radiology type as recorded by National Interim Clinical Imaging Procedure (NICIP) code.
Property 2 definition Radiology type as recorded by Systematized Nomenclature of Medicine (SNOMED) code.
Property 3 definition The PATIENT_SOURCE_SETTINGS field from the DIDs table is used.
Date definition PROCEDURE_DATE_CANCER_IMAGING in the DIDs data table is used.
Trust definition The SITE_CODE_OF_IMAGING field in the DIDs table are used.
Data source The DIDs data table is CASREF02.DIDS.DIDS_ANALYSIS
Further methodology The events are patient-linked to the tumour cohort. Events prior to a year before diagnosis are screened out.
DQ/Completeness Issues The DIDs data is thought to be less complete for radiology with dates in 2012 and early 2013. There is known undercounting for patients diagnosed in 2015 and imaging in 2016. The data is largely incomplete after 2017
Notes for interpretation Trusts vary in their use of NICIP vs SNOMED coding - it is advisable to use both to capture a particular class of radiology.

Field or property Description
Event name HES Admitted Patient Care episode
Event number 504
Date updated 12/05/2025
Linkage Patient
Event definition An episode of care as an inpatient, as recorded in the Hospital Episodes Statistics (HES) Admitted Patient Care (APC) dataset
Property 1 definition The ICD-10 code for the primary diagnosis of the patient in the episode.
Property 2 definition Treatment speciality for the episode as recorded in the TRETSPEF field, then a colon character, then the admimeth (admission method) value for the episode
Property 3 definition All ICD-10 diagnostic codes aggregated together in a list, separated by “:”
Date definition The EPISTART and EPIEND fields are used to identify the beginning and end of the episode
Trust definition The PROCODE3 field in the HESAPC field is used.
Data source The HES table is HESLIVE.HESAPC, the diagnosis codes are stored in HESLIVE.HESAPC_DIAG. Data is also drawn from HESLIVE.HESAPC_PROVISIONAL with diagnosis codes in HESLIVE.HESAPC_DIAG_PROVISIONAL.
Further methodology A linkage table HES_LINKAGE_AV_APC is used to link on PATIENTID from the patient cohort table. Another linkage table HESLIVE.HES_LINKAGE_AV_APC_PROVISIONAL is used to link to more recent data. Events prior to a year before diagnosis are screened out.
DQ/Completeness Issues Data is considered complete from April 2000.
Notes for interpretation Procedure and operation coding are performed by the coding teams at each trust and may vary in quality.

Field or property Description
Event name HES A&E attendance
Event number 505
Date updated 12/05/2025
Linkage Patient
Event definition An attendance at Accident and Emergency (A&E)
Property 1 definition The diagnosis code for the attendence captured in the DIAG2 field.
Property 2 definition N/A
Property 3 definition N/A
Date definition The arrival date at A&E given by the ARRIVALDATE_RAW field.
Trust definition The PROCODE3 field is used.
Data source The HES table is HESLIVE.HESAE, the diagnosis codes are stored in HESLIVE.HESAE_DIAG.
Further methodology A linkage table HES_LINKAGE_AV_AE is used to link on PATIENTID from the patient cohort table. Another linkage table HESLIVE.HES_LINKAGE_AV_AE_PROVISIONAL is used to link to more recent data. Events prior to a year before diagnosis are screened out.
DQ/Completeness Issues Data is considered complete from April 2007. Data series ends in March 2020.
Notes for interpretation Procedure and operation coding are performed by the coding teams at each trust and vary substantially in quality and completeness.

Field or property Description
Event name ENCR Diagnosis
Event number 506
Date updated 12/05/2025
Linkage Tumour
Event definition This event marks the diagnosis as registered by the NDRS cancer registration system following international standard European Network of Cancer Registration (ENCR) rules.
Property 1 definition The basisofdiagnosis field held within the CAS AT_TUMOUR table is used (see “Data source”).
Property 2 definition The 3-character ICD-10 code assigned to the tumour by the NCRAS cancer registration process.
Property 3 definition The “STAGE_BEST” field held within the CAS AT_TUMOUR_ENGLAND table used (see “Data source”) .
Date definition DIAGNOSISDATEBEST from AT_TUMOUR_ENGLAND (see “Data source”) is used.
Trust definition DIAG_TRUST from AT_TUMOUR_ENGLAND (see “Data source”) is used.
Data source ANALYSISNCR.AT_TUMOUR_ENGLAND from the snapshot on which the AT_PATHWAY table is built.
Further methodology The patient cohort table is linked by TUMOURID to the Data source tables listed and the fields listed are extracted.
DQ/Completeness Issues This event is complete for all cancer patients. The ENCR rules privilege pathological information over other sources of diagnostic information (such as radiology). In a minority of cases (~10% depending on cancer type) this may lead to the apparent diagnosisdate post-dating clinical activity such as MDT, decision to treat, or even treatment.
Notes for interpretation Also see event 600, which is derived based on this event, but with the intention of marking the first point at which we can be reasonably certain that a diagnosis has been made.

Field or property Description
Event name CWT Active Monitoring
Event number 507
Date updated 12/05/2025
Linkage Tumour
Event definition The start of active monitoring as captured by the Cancer Waiting Times (CWT) system.
Property 1 definition CTE Type
Property 2 definition N/A
Property 3 definition N/A
Date definition Treat Start date.
Trust definition The ORG_TREAT_START code from the CWT treatments table is used.
Data source The CWT data table is CASREF02.CWTPROC.TREATMENTS. The linkage table is lnk_tums_cwttrts.
Further methodology CWT records with modality 08 (active monitoring) are identified. This field holds tumour-linked data, using the tumour linkage table specified in the data source.
DQ/Completeness Issues No known issues, but DQ not well investigated.
Notes for interpretation

Field or property Description
Event name Major Surgery
Event number 508
Date updated 12/05/2025
Linkage Patient
Event definition Major surgery events from HES (restricted to within a year before the diagnosis).
Property 1 definition OPCS code of resection
Property 2 definition N/A
Property 3 definition N/A
Date definition Surgery date from APC HES, using previously established major surgery codes.
Trust definition The provider code PROCODE3 from HES APC or OP is used.
Data source The HES table is HESLIVE.HESAPC and HESLIVE.HESOP, the procedure codes are stored in HESLIVE.HESAPC_OPERTN and HESLIVE.HESOP_OPERTN
Further methodology Lookup table AV2021.opcs4resection_lookup_13_21 is used to implement CASSOP 4.9 to identify specific OPCS codes for major surgery by cancer site. Stage-specific major surgery is identified using AVP_TEST_HES_LUT and AVP_TEST_STAGE_LUT. A linkage table HES_LINKAGE_AC_APC is used to link on PATIENTID from the patient cohort table. Events prior to a year before diagnosis are screened out.
DQ/Completeness Issues No surgery is reported where the cancer site has not had major surgery codes associated with it, as defined in CASSOP 4.9.
Notes for interpretation

Field or property Description
Event name RTDS appointment (pre 201604)
Event number 509
Date updated 12/05/2025
Linkage Patient
Event definition Radiotherapy fractions before April 2016.
Property 1 definition PRESCRIBEDFRACTIONS field from RTDS prescriptions table
Property 2 definition RTPRESCRIBEDDOSE field from RTDS prescriptions table
Property 3 definition RTTREATMENTANATOMICALSITE field from RTDS prescriptions table
Date definition Appointment date from RTDS OPCDS_PROCEDURE table.
Trust definition The provider organisation code from the RTDS prescriptions table is used.
Data source The RTDS table (pre April 2016) is RTDS2016.RTDS_PRESCRIPTIONS.
Further methodology A linkage table RTDS2016.OPCDS_CAS1712_LINKAGE is used to link on PATIENTID from the patient cohort table. Events prior to a year before diagnosis are screened out.
DQ/Completeness Issues Data was curated by NatCanSAT, their methodology is unavailable, but this data is belived to be a mixture of aggregated episode and disaggregated fraction data.
Notes for interpretation This is a single event which marks the delivery of one or multiple fractions of radiotherapy (teletherapy only). It is based on RTDS data originally collected by NatCanSAT up to March 31st 2016.

Field or property Description
Event name SACT regimen start
Event number 510
Date updated 12/05/2025
Linkage Patient
Event definition Start of SACT regimen.
Property 1 definition Benchmark regimen
Property 2 definition Intent of treatment
Property 3 definition ANALYSIS_GROUP field
Date definition Regimen start date.
Trust definition The provider organisation code from the SACT tumour table is used.
Data source The SACT regimen table is SACT_LEGACY.REGIMEN, and SACT.AT_REGIMEN_ENGLAND for more recent data.
Further methodology The events are patient-linked to the tumour cohort. Events prior to a year before diagnosis are screened out.
DQ/Completeness Issues Data collection was mandatory from April 2014 and known to be less complete before that. Treatment for haemotology and paedeatric cancers are known to be less complete. Some patients may have a regimen recorded for each cycle.
Notes for interpretation This is a single event which marks the start of the delivery of a series of cycles of chemotherapy.

Field or property Description
Event name Vital Status
Event number 511
Date updated 12/05/2025
Linkage Patient
Event definition Vital status
Property 1 definition Vital status code (mostly A/D for Alive/Dead)
Property 2 definition Underlying cause of death.
Property 3 definition Death location
Date definition Vital statusdate (where the patient has died this is the date of death from ONS).
Trust definition Not populated
Data source AV_PATIENT in the latest CAS snapshot.
Further methodology
DQ/Completeness Issues No known issues. A batch trace is carried out quarterly to pick up deaths recorded in cases diagnosed up to that point. Deaths can be considered complete to approximately six weeks prior to the time of last trace. Where a coroner’s inquest is needed (e.g. suicide, or asbestos related mesothelioma) reporting of deaths may be delayed and therefore undercounted in the most recent data.
Notes for interpretation Death data is as recorded by ONS.

Field or property Description
Event name Cancer Treatment Period Start
Event number 512
Date updated 12/05/2025
Linkage Tumour
Event definition Start of cancer treatment period from the Cancer Waiting Times (CWT) system.
Property 1 definition CTE_Type
Property 2 definition N/A
Property 3 definition N/A
Date definition Treatment period start date from CWT.
Trust definition ORG_DEC_TO_TREAT from the CWTPROC.TREATMENTS table is used.
Data source The CWT data table is CASREF02.CWTPROC.TREATMENTS. The linkage table is lnk_tums_cwttrts.
Further methodology The event is populated from the TREAT_PERIOD_START date. Events prior to a year before diagnosis are screened out.
DQ/Completeness Issues This is a mandatory field in the CWT dataset, however only ~75% of registered cancer cases are recorded in the CWT database.
Notes for interpretation This marks the date that the patient and consultant agreed the course of the treatment (also known as the ‘Decision to Treat’ date).

Field or property Description
Event name Cancer Treatment
Event number 513
Date updated 12/05/2025
Linkage Tumour
Event definition Treatment start date from Cancer Waiting Times (CWT) system.
Property 1 definition Treatment modality
Property 2 definition CTE_TYPE
Property 3 definition METS_SITE
Date definition Treatment start date from CWT.
Trust definition ORG_TREAT_START from the CWTPROC.TREATMENTS table is used.
Data source The CWT data table is CASREF02.CWTPROC.TREATMENTS. The linkage table is lnk_tums_cwttrts.
Further methodology The event is populated from the TREAT_START date. Events prior to a year before diagnosis are screened out.
DQ/Completeness Issues This is a mandatory field in the CWT dataset, however only ~75% of registered cancer cases are recorded in the CWT database.
Notes for interpretation The first cancer treatment marks the ‘clock stop’ for the 31-day and 62-day waiting time targets.

Field or property Description
Event name Outpatient attendence
Event number 514
Date updated 12/05/2025
Linkage Patient
Event definition Outpatient attendance from HES.
Property 1 definition Mainspef of clinician leading clinic
Property 2 definition All opcs4 codes aggreagated together with a seperator of “:”
Property 3 definition Code for whether the patient attended or not - ATTENDED field
Date definition Attendance date from HES OP data.
Trust definition PROCODET from the HESOP table is used.
Data source The HES table is HESLIVE.HESOP. Data is also drawn from HESLIVE.HESOP_PROVISIONAL.
Further methodology A linkage table HES_LINKAGE_AV_OP is used to link on PATIENTID from the patient cohort table. Another linkage table HESLIVE.HES_LINKAGE_AV_OP_PROVISIONAL is used to link to more recent data. Events prior to a year before diagnosis or before 2012 are screened out.
DQ/Completeness Issues Includes Did-Not-Attend apponitments, may occur after death if hospital did not cancel appointments on patient mortality.
Notes for interpretation

Field or property Description
Event name MDT: COSD
Event number 515
Date updated 12/05/2025
Linkage Tumour
Event definition MDT derived from COSD data.
Property 1 definition MDT type (local/specialist) : MDTDISCUSSIONINDICATOR field
Property 2 definition N/A
Property 3 definition N/A
Date definition MDT date from COSD.
Trust definition Provider code from the event table is used.
Data source The table used is SPRINGMVC3.CANCERCAREPLAN from the snapshot the pathway is built against. Trust codes are drawn from SPRINGMVC3.EVENT.
Further methodology The events are tumour-linked to the tumour cohort. Events prior to a year before diagnosis are screened out.
DQ/Completeness Issues Around 80% of patients have a MDT date reported, it is not known whether this is due to missing data or reflects a fact that some patients are not going through MDT.
Notes for interpretation Date of MDT as reported by trusts in their COSD submissions. Patients may be discussed at multiple MDTs during period of diagnosis and initial treatment, and after treatment in the followup period.

Field or property Description
Event name Other tumour diagnosis
Event number 516
Date updated 12/05/2025
Linkage Patient
Event definition Other primary tumour events.
Property 1 definition Basis of diagnosis
Property 2 definition Tumour ICD-10 code
Property 3 definition Stage Best field
Date definition Diagnosis date of other tumour in same patient.
Trust definition DIAGNOSISPROVIDER_CODE from the AV tumour experimental table is used.
Data source ANALYSISNCR.AT_TUMOUR_ENGLAND from the snapshot on which the Pathway is built.
Further methodology The patient cohort table is linked by PATIENTID to the Data source tables listed and TUMOURID is used to select other tumours and the fields listed are extracted.
DQ/Completeness Issues Based on cancer registry data, completeness likely to be ~>98%.
Notes for interpretation Other primary tumours will be associated with their own tumour pathway, or if close enough in time the two pathways may ‘merge’ as the patient is treated concurrently (or consecutively) for multiple primaries,

Field or property Description
Event name CT from AV_TREATMENT
Event number 517
Date updated 12/05/2025
Linkage Tumour
Event definition Cancer treatment recorded in AV treatment table.
Property 1 definition OPCS4 code
Property 2 definition EVENT CODE from AV_Treatment
Property 3 definition N/A
Date definition Event date
Trust definition TRUST_CODE from the AV treatment table is used.
Data source ANALYSISNCR.AT_TREATMENT_ENGLAND from the snapshot on which the Pathway is built.
Further methodology Chemotherapy is identified by choosing events where the EVENTCODE is one of (‘02’,‘04’,‘15’,‘19’,‘21’,‘CTX’,‘02_03’,‘02_15’,‘02_21’,‘15_21’). Events prior to a year before diagnosis are screened out.
DQ/Completeness Issues Date may align with the start of the regimen, first cycle, or other significant date close to the commencement of chemotherapy.
Notes for interpretation Typically a single event marking the start chemotherapy treatment.

Field or property Description
Event name RT from AV_TREATMENT
Event number 518
Date updated 12/05/2025
Linkage Tumour
Event definition Radiotherapy treatment recorded in AV treatment table.
Property 1 definition OPCS4 code
Property 2 definition EVENT CODE from AV_Treatment
Property 3 definition N/A
Date definition Event date
Trust definition TRUST_CODE from the AV treatment table is used.
Data source ANALYSISNCR.AT_TREATMENT_ENGLAND from the snapshot on which the Pathway is built.
Further methodology Radiotherapy is identified by choosing events where the EVENTCODE is one of (‘04’,‘05’,‘22’,‘RTX’). Events prior to a year before diagnosis are screened out.
DQ/Completeness Issues Date may align with the start of the appointment or the first/an early fraction delivered.
Notes for interpretation Typically a single event marking the start radiotherapy treatment.

Field or property Description
Event name Surgery from AV_TREATMENT
Event number 519
Date updated 12/05/2025
Linkage Tumour
Event definition All surgery events recorded in AV treatment table.
Property 1 definition OPCS4 code
Property 2 definition EVENT CODE from AV_Treatment
Property 3 definition N/A
Date definition Event date
Trust definition TRUST_CODE from the AV treatment table is used.
Data source ANALYSISNCR.AT_TREATMENT_ENGLAND from the snapshot on which the Pathway is built.
Further methodology Surgery is identified by choosing events where the EVENTCODE is one of (‘01a’,‘01b’,‘01c’,‘01z’). Events prior to a year before diagnosis are screened out.
DQ/Completeness Issues No known issues
Notes for interpretation All surgeries recorded by the cancer registry, which is limited to those considered relevant to cancer treatment and includes paliative and supportive surgery.

Field or property Description
Event name Major Surgery from AV_TREATMENT
Event number 520
Date updated 12/05/2025
Linkage Tumour
Event definition Major surgery events recorded in AV treatment table.
Property 1 definition OPCS4 code
Property 2 definition EVENT CODE from AV_Treatment
Property 3 definition N/A
Date definition Event date
Trust definition TRUST_CODE from the AV treatment table is used.
Data source ANALYSISNCR.AT_TREATMENT_ENGLAND from the snapshot on which the Pathway is built.
Further methodology Surgery is identified by choosing events where the EVENTCODE is one of (‘01a’,‘01b’,‘01c’,‘01z’). Lookup table AV2021.opcs4resection_lookup_13_21 is used to implement CASSOP 4.9 to identify specific OPCS codes for major surgery by cancer site. Stage-specific major surgery is identified using AVP_TEST_AVT_LUT and AVP_TEST_STAGE_LUT. Events prior to a year before diagnosis are screened out.
DQ/Completeness Issues No known issues
Notes for interpretation All resective surgeries recorded by the cancer registry, defined according to CASSOP 4.9.

Field or property Description
Event name SACT cycle event
Event number 521
Date updated 12/05/2025
Linkage Patient
Event definition Start of SACT cycle.
Property 1 definition Benchmark regimen
Property 2 definition Cycle number
Property 3 definition Performance status at start of cycle, concatenated with performance status as start of regimen
Date definition Cycle start date
Trust definition ORGANISATION_CODE_OF_PROVIDER from the SACT tumour table is used.
Data source The SACT cycle table is SACT_LEGACY.cycle up to 2017-06-30 and SACT.AT_REGIMEN_ENGLAND from the latest snapshot after that.
Further methodology The events are patient-linked to the tumour cohort. Events prior to a year before diagnosis are screened out.
DQ/Completeness Issues Data collection was mandatory from April 2014 and known to be less complete before that. Treatment for haemotology and paedeatric cancers are known to be less complete. Data quality can vary strongly by trust - e.g. some trusts may only submit the first cycle. Use caution in interpreting.
Notes for interpretation Events with a BENCHMARK_GROUP in (‘NOT CHEMO’,‘HORMONES’,‘ZOLEDRONIC ACID’,‘PAMIDRONATE’,‘DENOSUMAB’) are filtered out.

Field or property Description
Event name SACT drug event
Event number 522
Date updated 12/05/2025
Linkage Patient
Event definition SACT drug given.
Property 1 definition Benchmark regimen
Property 2 definition Drug group
Property 3 definition Administration route
Date definition ADMINISTRATION_DATE
Trust definition ORG_CODE_OF_DRUG_PROVIDER from the SACT drug detail table is used.
Data source The SACT drug administration table is SACT_LEGACY.drug_detail up to 2017-06-30 and SACT.AT_DRUG_DETAIL_ENGLAND from the latest snapshot after that..
Further methodology The events are patient-linked to the tumour cohort. Events prior to a year before diagnosis are screened out.
DQ/Completeness Issues Data collection was mandatory from April 2014 and known to be less complete before that. Treatment for haemotology and paedeatric cancers are known to be less complete. Data quality can vary strongly by trust. Use caution in interpreting.
Notes for interpretation Events with a BENCHMARK_GROUP in (‘NOT CHEMO’,‘HORMONES’,‘ZOLEDRONIC ACID’,‘PAMIDRONATE’,‘DENOSUMAB’) are filtered out.

Field or property Description
Event name Hormone from AV_TREATMENT
Event number 523
Date updated 12/05/2025
Linkage Tumour
Event definition Hormone treatment recorded in AV treatment table.
Property 1 definition OPCS4 code
Property 2 definition EVENT CODE from AV_Treatment
Property 3 definition N/A
Date definition Event date
Trust definition TRUST_CODE from the AV treatment table is used.
Data source ANALYSISNCR.AT_TREATMENT_ENGLAND from the snapshot on which the Pathway is built.
Further methodology Hormone therapy is identified by choosing events where the EVENTCODE is in (‘03’,‘03_15’,‘03_21’). Events prior to a year before diagnosis are screened out.
DQ/Completeness Issues Known to be very incomplete, approximately 50%. Large regional variation with much higher rates reported in the Yorkshire area for historic reasons.
Notes for interpretation We hope to supplement this with data from the prescriptions dataset, but the timescale for this is not determined.

Field or property Description
Event name Brachy from AV_TREATMENT
Event number 524
Date updated 12/05/2025
Linkage Tumour
Event definition Brachytherapy recorded in AV treatment table.
Property 1 definition OPCS4 code
Property 2 definition EVENT CODE from AV_Treatment
Property 3 definition N/A
Date definition Event date
Trust definition TRUST_CODE from the AV treatment table is used.
Data source ANALYSISNCR.AT_TREATMENT_ENGLAND from the snapshot on which the Pathway is built.
Further methodology Brachytherapy is identified by choosing events where the EVENTCODE is 06. Events prior to a year before diagnosis are screened out.
DQ/Completeness Issues No known issues, but DQ not well investigated.
Notes for interpretation

Field or property Description
Event name Biopsy
Event number 525
Date updated 18/06/2025
Linkage Tumour
Event definition Biopsy recorded in COSD.
Property 1 definition OPCS4 code
Property 2 definition N/A
Property 3 definition N/A
Date definition Event date
Trust definition Provider code from the event table is used.
Data source The table used is SPRINGMVC3.SURGERYETC from the snapshot the pathway is built against. Trust codes are drawn from SPRINGMVC3.EVENT.
Further methodology Lookup table OPCS4DIAGNOSTICCODES_V_1_5 with the BX flag set is used to identify biopsy diagnostic events. Events are included when the date and trust fields are complete.
DQ/Completeness Issues Severely under-reports realistic numbers of biopsies that must be occurring.
Notes for interpretation

Field or property Description
Event name Endoscopy from COSD
Event number 526
Date updated 18/06/2025
Linkage Tumour
Event definition Endoscopy event recorded in COSD.
Property 1 definition OPCS4 code
Property 2 definition N/A
Property 3 definition N/A
Date definition Event date
Trust definition Provider code from the event table is used.
Data source The table used is SPRINGMVC3.SURGERYETC from the snapshot the pathway is built against. Trust codes are drawn from SPRINGMVC3.EVENT.
Further methodology Lookup table OPCS4DIAGNOSTICCODES_V_1_5 with the LD flag set is used to identify endoscopy diagnostic events. Events are included when the date and trust fields are complete.
DQ/Completeness Issues No known issues, but DQ not well investigated.
Notes for interpretation

Field or property Description
Event name COSD Pathology
Event number 527
Date updated 18/06/2025
Linkage Tumour
Event definition Pathology event recorded in COSD.
Property 1 definition Indication of date used: taken/receipt/ investigation
Property 2 definition pathologyinvestigationtype
Property 3 definition N/A
Date definition The first date available of SAMPLETAKENDATE, SAMPLERECEIPTDATE and INVESTIGATIONRESULTDATE.
Trust definition Provider code from the event table is used.
Data source The table used is SPRINGMVC3.PATHOLOGY from the snapshot the pathway is built against. Trust codes are drawn from SPRINGMVC3.EVENT.
Further methodology The events are tumour-linked to the tumour cohort, and presented where the date is available. Events prior to 2012 are excluded.
DQ/Completeness Issues No known issues, complete for ~85% of cancers.
Notes for interpretation

Field or property Description
Event name RTD start point
Event number 528
Date updated 18/06/2025
Linkage Tumour
Event definition Date first seen from routes to diagnosis.
Property 1 definition N/A
Property 2 definition N/A
Property 3 definition N/A
Date definition Date of HES record.
Trust definition PROCODET from the HESLIVE table is used.
Data source Data is drawn from RTD snapshots under RTD2020.
Further methodology The events are tumour-linked to the tumour cohort, and presented where the date in HES is available.
DQ/Completeness Issues Defined for patients with a HES episode as the start point of the Route to Diagnosis
Notes for interpretation See http://www.ncin.org.uk/publications/routes_to_diagnosis for more information

Field or property Description
Event name RTD referral date
Event number 529
Date updated 18/06/2025
Linkage Tumour
Event definition Referral date from routes to diagnosis (outpatient route).
Property 1 definition N/A
Property 2 definition N/A
Property 3 definition N/A
Date definition Referral date held in HES OP.
Trust definition PROCODET from the HESLIVE table is used.
Data source Data is drawn from RTD snapshots under RTD2020.
Further methodology The events are tumour-linked to the tumour cohort, and presented where the date in HES is available. TODO: Route-code caveat I don’t quite follow.
DQ/Completeness Issues Defined for patients with a outpatient HES episode as the start point of the route.
Notes for interpretation See http://www.ncin.org.uk/publications/routes_to_diagnosis for more information

Field or property Description
Event name MDT: CWT
Event number 530
Date updated 18/06/2025
Linkage Tumour
Event definition MDT derived from Cancer Waiting Times (CWT) system.
Property 1 definition MDT type (local/specialist)
Property 2 definition N/A
Property 3 definition N/A
Date definition MDT date from CWT.
Trust definition ORG_DEC_TO_TREAT from the CWTPROC treatments table is used.
Data source The CWT data table is CASREF02.CWTPROC.TREATMENTS. The linkage table is lnk_tums_cwttrts.
Further methodology The event is populated from the MDT_DATE date. Events prior to a year before diagnosis are screened out.
DQ/Completeness Issues Only 70-80% of registered cancer cases are recorded in the CWT database.
Notes for interpretation

Field or property Description
Event name Biopsy from APC HES
Event number 531
Date updated 18/06/2025
Linkage Patient
Event definition Biopsy recorded in HES APC data.
Property 1 definition OPCS code
Property 2 definition N/A
Property 3 definition N/A
Date definition HESAPC OPDATE
Trust definition PROCODE3 from the HESLIVE APC table is used.
Data source The HES table is HESLIVE.HESAP. Data is also drawn from HESLIVE.HESAPC_PROVISIONAL.
Further methodology The events are patient-linked to the tumour cohort. Lookup table OPCS4DIAGNOSTICCODES_V_1_5 with the BX flag set is used to identify biopsy diagnostic events. Events are included when the date and trust fields are complete. Events prior to a year before diagnosis are screened out.
DQ/Completeness Issues Severely under-reports realistic numbers of biopsies that must be occurring.
Notes for interpretation This field is under review, usage not currently recommended

Field or property Description
Event name Endoscopy from HES
Event number 532
Date updated 18/06/2025
Linkage Patient
Event definition Endoscopy event recorded in HES.
Property 1 definition OPCS4 code
Property 2 definition N/A
Property 3 definition N/A
Date definition HESAPC OPDATE
Trust definition PROCODE3 from the HESLIVE APC table is used.
Data source The HES table is HESLIVE.HESAP. Data is also drawn from HESLIVE.HESAPC_PROVISIONAL.
Further methodology The events are patient-linked to the tumour cohort. Lookup table OPCS4DIAGNOSTICCODES_V_1_5 with the LD flag set is used to identify endoscopy diagnostic events. Events are included when the date and trust fields are complete. Events prior to a year before diagnosis are screened out.
DQ/Completeness Issues No known issues, but DQ not well investigated.
Notes for interpretation This has been closely examined for colorectal and lung cancers, other cancers may have less complete endocopy code lists.

Field or property Description
Event name Active monitoring from COSD
Event number 533
Date updated 18/06/2025
Linkage Tumour
Event definition Active monitoring recorded in COSD.
Property 1 definition Monitoring intent (1: future curative, 2: future palliative, 3: future unknown/uncertain)
Property 2 definition N/A
Property 3 definition N/A
Date definition STARTORADMISSIONDATE1
Trust definition Provider code from the SPRINGMVC3.EVENT table is used.
Data source The table used is SPRINGMVC3.ACTIVEMONITORING from the snapshot the pathway is built against. Trust codes are drawn from SPRINGMVC3.EVENT, SPRINGMVC3.TUMOUREVENTS is used for tumour-level linkage and SPRINGMVC3.TREATMENT is used for the date.
Further methodology The events are tumour-linked to the tumour cohort, and presented where the date is available. Events prior to 2012 are excluded.
DQ/Completeness Issues No known issues, but DQ not well investigated.
Notes for interpretation

Field or property Description
Event name Path sample taken
Event number 534
Date updated 18/06/2025
Linkage Tumour
Event definition Date the pathology sample was taken as recorded in COSD.
Property 1 definition N/A
Property 2 definition N/A
Property 3 definition N/A
Date definition SAMPLETAKENDATE
Trust definition Provider code from the SPRINGMVC3.EVENT table is used.
Data source The table used is SPRINGMVC3.PATHOLOGY from the snapshot the pathway is built against. Trust codes are drawn from SPRINGMVC3.EVENT.
Further methodology The events are patient-linked to the tumour cohort, and presented where the date is available.
DQ/Completeness Issues Complete for ~55% of tumours
Notes for interpretation

Field or property Description
Event name Path sample received
Event number 535
Date updated 18/06/2025
Linkage Tumour
Event definition Receipt of the pathology sample as recorded in COSD.
Property 1 definition N/A
Property 2 definition N/A
Property 3 definition N/A
Date definition SAMPLERECEIPTDATE
Trust definition Provider code from the SPRINGMVC3.EVENT table is used.
Data source The table used is SPRINGMVC3.PATHOLOGY from the snapshot the pathway is built against. Trust codes are drawn from SPRINGMVC3.EVENT.
Further methodology The events are patient-linked to the tumour cohort, and presented where the date is available.
DQ/Completeness Issues Complete for ~75% if tumours
Notes for interpretation

Field or property Description
Event name Path investigation result
Event number 536
Date updated 18/06/2025
Linkage Tumour
Event definition Result of the pathology sample as recorded in COSD.
Property 1 definition N/A
Property 2 definition N/A
Property 3 definition N/A
Date definition INVESTIGATIONRESULTDATE
Trust definition Provider code from the SPRINGMVC3.EVENT table is used.
Data source The table used is SPRINGMVC3.PATHOLOGY from the snapshot the pathway is built against. Trust codes are drawn from SPRINGMVC3.EVENT.
Further methodology The events are patient-linked to the tumour cohort, and presented where the date is available.
DQ/Completeness Issues Complete for ~65% if tumours
Notes for interpretation

Field or property Description
Event name RTDS episode (post 201604)
Event number 537
Date updated 18/06/2025
Linkage Patient
Event definition Beginning of radiotherapy episode from April 2016.
Property 1 definition Radiotherapy intent
Property 2 definition N/A
Property 3 definition N/A
Date definition TREATMENTSTARTDATE
Trust definition ORGPROVIDER from the RTDS episodes table is used.
Data source The RTDS table (from April 2016) is RTDS.AT_EPISODES and RTDS.AT_PRESCRIPTIONS from the snapshot the pathway is built against.
Further methodology The events are patient-linked to the tumour cohort, and presented where the date is available. Events prior to a year before diagnosis are screened out.
DQ/Completeness Issues There is intermittant under-reporting by trust in the last few months of recorded data as the RTDS team actively follow up trust by trust.
Notes for interpretation Marks the beginning of the delivery of a series of teletherapy fractions. It is based on RTDS data originally collected by NCRAS from April 1st 2016. Welsh providers are excluded.

Field or property Description
Event name RTDS appointment (post 201604)
Event number 538
Date updated 18/06/2025
Linkage Patient
Event definition Radiotherapy fractions from April 2016.
Property 1 definition Prescribed fractions
Property 2 definition Prescribed dose
Property 3 definition Treatment anatomicalsite
Date definition APPTDATE
Trust definition ORGPROVIDER from the RTDS episodes table is used.
Data source The RTDS table (from 201604) is RTDS.AT_EPISODES and RTDS.AT_PRESCRIPTIONS from the snapshot the pathway is built against.
Further methodology The events are patient-linked to the tumour cohort, and presented where the date is available. Events prior to a year before diagnosis are screened out.
DQ/Completeness Issues There is intermittant under-reporting by trust in the last few months of recorded data as the RTDS team actively follow up trust by trust.
Notes for interpretation This is a single event which marks the delivery of a fraction of radiotherapy (teletherapy only). It is based on RTDS data originally collected by NCRAS from April 1st 2016. Welsh providers are excluded.

Field or property Description
Event name RTDS episode (pre 201604)
Event number 539
Date updated 18/06/2025
Linkage Patient
Event definition Beginning of radiotherapy episode before April 2016.
Property 1 definition Radiotherapy intent
Property 2 definition N/A
Property 3 definition N/A
Date definition APPTDATE
Trust definition ORGPROVIDER from the RTDS episodes table is used.
Data source The RTDS table (pre 201604) is RTDS2016.RTDS_EPISODES.
Further methodology A linkage table RTDS2016.OPCDS_AV_TUMOUR_LINKAGE is used to link on PATIENTID from the patient cohort table to RTDS2016.RTDS_PRESCRIPTIONS, unique episodes corresponding to those prescriptions are the identified. Events prior to a year before diagnosis are screened out.
DQ/Completeness Issues No known issues, but DQ not well investigated.
Notes for interpretation Marks the beginning of the delivery of a series of teletherapy fractions. It is based on RTDS data originally collected by NatCanSAT up to March 31st 2016.

Field or property Description
Event name HESAPC procedures
Event number 540
Date updated 18/06/2025
Linkage Patient
Event definition HESAPC procedures
Property 1 definition List of procedure codes aggregated together in a list, separated by “:”
Property 2 definition N/A
Property 3 definition N/A
Date definition Operation date (one event is generated per unique operation date in the episode)
Trust definition Provider code for the episode
Data source The HES table is HESLIVE.HESAPC, the diagnosis codes are stored in HESLIVE.HESAPC_DIAG. Data is also drawn from HESLIVE.HESAPC_PROVISIONAL with diagnosis codes in HESLIVE.HESAPC_DIAG_PROVISIONAL.
Further methodology A linkage table HES_LINKAGE_AV_APC is used to link on PATIENTID from the patient cohort table. Another linkage table HESLIVE.HES_LINKAGE_AV_APC_PROVISIONAL is used to link to more recent data. Events prior to a year before diagnosis are screened out.
DQ/Completeness Issues Data is considered complete from April 2000.
Notes for interpretation Procedure and operation coding are performed by the coding teams at each trust and may vary in quality.

Field or property Description
Event name AV_TREATMENT imaging
Event number 549
Date updated 18/06/2025
Linkage Tumour
Event definition Imaging recorded in AV treatment table.
Property 1 definition IMAGINGCODE from AV_Treatment
Property 2 definition EVENT CODE from AV_Treatment
Property 3 definition N/A
Date definition Event date
Trust definition TRUST_CODE from the AV treatment table is used.
Data source ANALYSISNCR.AT_TREATMENT_ENGLAND from the snapshot on which the Pathway is built.
Further methodology Imaging is identified by choosing events where the EVENTCODE is ‘IM’. Events prior to a year before diagnosis are screened out.
DQ/Completeness Issues DQ has not been closely investigated
Notes for interpretation

Field or property Description
Event name AV_TREATMENT Other event
Event number 550
Date updated 18/06/2025
Linkage Tumour
Event definition Other treatment recorded in AV treatment table.
Property 1 definition N/A
Property 2 definition EVENT CODE from AV_Treatment
Property 3 definition N/A
Date definition Event date
Trust definition TRUST_CODE from the AV treatment table is used.
Data source ANALYSISNCR.AT_TREATMENT_ENGLAND from the snapshot on which the Pathway is built.
Further methodology Imaging is identified by choosing events where the EVENTCODE is in (‘07’,‘08’,‘09’,‘10’,‘11’,‘12’,‘13’,‘14’,‘16’,‘20’,‘2000’,‘21’,‘97’,‘98’,‘99’). Events prior to a year before diagnosis are screened out.
DQ/Completeness Issues DQ has not been closely investigated
Notes for interpretation

Field or property Description
Event name RTDS brachytherapy fractions up to April 2016
Event number 551
Date updated 18/06/2025
Linkage Patient
Event definition One event for each brachytherapy fraction recorded
Property 1 definition PRESCRIBEDFRACTIONS
Property 2 definition RTPRESCRIBEDDOSE
Property 3 definition RTTREATMENTANATOMICALSITE
Date definition APPTDATE
Trust definition ORGCODEPROVIDER
Data source RTDS2016.RTDS_PRESCRIPTIONS
Further methodology
DQ/Completeness Issues DQ has not been closely investigated
Notes for interpretation

Field or property Description
Event name RTDS brachytherapy fractions from April 2016
Event number 552
Date updated 18/06/2025
Linkage Patient
Event definition One event for each brachytherapy episode recorded
Property 1 definition RADIOTHERAPYINTENT
Property 2 definition N/A
Property 3 definition N/A
Date definition TREATMENTSTARTDATE
Trust definition ORGCODEPROVIDER
Data source RTDS.AT_EPISODES_ENGLAND from the snapshot on which the Pathway is built.
Further methodology
DQ/Completeness Issues DQ has not been closely investigated
Notes for interpretation

Field or property Description
Event name RTDS brachytherapy appointments from April 2016
Event number 553
Date updated 18/06/2025
Linkage Patient
Event definition One event for each brachytherapy appointment recorded
Property 1 definition PRESCRIBEDFRACTIONS
Property 2 definition RTPRESCRIBEDDOSE
Property 3 definition RTTREATMENTANATOMICALSITE
Date definition APPTDATE
Trust definition ORGCODEPROVIDER
Data source RTDS.AT_PRESCRIPTIONS_ENGLAND from the snapshot on which the Pathway is built.
Further methodology
DQ/Completeness Issues DQ has not been closely investigated
Notes for interpretation

Field or property Description
Event name RTDS brachytherapy episodes up to April 2016
Event number 554
Date updated 18/06/2025
Linkage Patient
Event definition One event for each brachytherapy episode recorded
Property 1 definition RADIOTHERAPYINTENT
Property 2 definition N/A
Property 3 definition N/A
Date definition TREATMENTSTARTDATE
Trust definition ORGCODEPROVIDER
Data source RTDS2016.RTDS_EPISODES
Further methodology
DQ/Completeness Issues DQ has not been closely investigated
Notes for interpretation

Field or property Description
Event name Derived Diagnosis date
Event number 600
Date updated 18/06/2025
Linkage Tumour
Event definition Derived diagnosis date. Must satisfy the following rules: 1. The derived diagnosis date must be before or on the same date as the Cancer treatment period start date; 2. The derived diagnosis date must be before or on the same date as the MDT date; 3. The derived diagnosis date must be before or on the same date as first treatment of any kind; 4. It must not be more than han 90 days prior to current diagnosisdate.
Property 1 definition PROPERTY_1 of event used.
Property 2 definition PROPERTY_2 of event used
Property 3 definition Event_TYPE of EVENT used
Date definition First of diagnosis, treatment, MDT, CTPSD
Trust definition The trust definition is derived from that of the event used.
Data source Derived events are based on existing events in the current AV_PATHWAY build.
Further methodology The events are tumour-linked to the tumour cohort. Event types 6,7,8,9,10,12,13,15,17,18,20,21,22,23,24,30,33,37,38,39 are used for this derived event.
DQ/Completeness Issues Complete for all tumours
Notes for interpretation About 10% of tumours (with strong variation by cancer type) differ in their derived and ENCR diagnosis date (i.e., event 6). The median variation is about a week.

Field or property Description
Event name Referral date
Event number 601
Date updated 18/06/2025
Linkage Tumour
Event definition Derived referral date - takes the first date between CWT referral and RTD referral.
Property 1 definition PROPERTY_1 of event used.
Property 2 definition PROPERTY_2 of event used
Property 3 definition PROPERTY_3 of event used
Date definition First of CWT referral and RTD startpoint. Ties for date are broken with AVPID.
Trust definition The trust definition is derived from that of the event used.
Data source Derived events are based on existing events in the current AV_PATHWAY build.
Further methodology The events are tumour-linked to the tumour cohort. Event types 1,29 are used for this derived event.
DQ/Completeness Issues
Notes for interpretation Experimental field under active development

Field or property Description
Event name First Seen
Event number 602
Date updated 18/06/2025
Linkage Tumour
Event definition Derived first seen date - takes the first date between CWT first seen date and RTD start point.
Property 1 definition PROPERTY_1 of event used.
Property 2 definition PROPERTY_2 of event used
Property 3 definition PROPERTY_3 of event used
Date definition First of CWT first seen and RTD start point. Ties for date are broken with AVPID.
Trust definition The trust definition is derived from that of the event used.
Data source Derived events are based on existing events in the current AV_PATHWAY build.
Further methodology The events are tumour-linked to the tumour cohort. Event types 2,28 are used for this derived event.
DQ/Completeness Issues
Notes for interpretation Experimental field under active development

Field or property Description
Event name Derived MDTs
Event number 603
Date updated 18/06/2025
Linkage Tumour
Event definition Derived MDT date - takes the first date between MDT from COSD and MDT from CWT.
Property 1 definition PROPERTY_1 of event used.
Property 2 definition PROPERTY_2 of event used
Property 3 definition PROPERTY_3 of event used
Date definition Date of first MDT, from COSD and CWT.
Trust definition The trust definition is derived from that of the event used.
Data source Derived events are based on existing events in the current AV_PATHWAY build.
Further methodology The events are tumour-linked to the tumour cohort. Event types 15,30 are used for this derived event.
DQ/Completeness Issues
Notes for interpretation First MDT date. This may pre- or post date treatment. Occasionally there is no recorded MDT in the initial diagnosis or treatment period and the ‘first’ MDT will be months later during the followup/recurrence period

Field or property Description
Event name Derived first treatment
Event number 604
Date updated 18/06/2025
Linkage Patient
Event definition Derived first treatment - must have minimum of SACT, major surgery, RTDS, CWT-TSD, hormone treatment, active monitoring, brachytherapy.
Property 1 definition Modality code
Property 2 definition EVENT_TYPE of event used
Property 3 definition N/A
Date definition First treatment date.
Trust definition Trust of event used
Data source Derived events are based on existing events in the current AV_PATHWAY build.
Further methodology The events are tumour-linked to the tumour cohort. Event types 7,8,9,10,13,17,18,20,21,22,23,24 are used for this derived event.
DQ/Completeness Issues
Notes for interpretation This event is generated by scanning the pathway from the point of daignosis looking for a ‘treatment’ type event.

Field or property Description
Event name Derived end of initial treatment
Event number 605
Date updated 18/06/2025
Linkage Patient
Event definition Derived end of initial treatment - looks for first gap in treatment of more than 182 days.
Property 1 definition Modality code
Property 2 definition EVENT_TYPE of event used
Property 3 definition N/A
Date definition Last treatment date before gap of >182 days.
Trust definition Trust of event used
Data source Derived events are based on existing events in the current AV_PATHWAY build.
Further methodology The events are tumour-linked to the tumour cohort. Event types 7,8,9,10,13,17,18,20,21,22,23,24 are used for this derived event.
DQ/Completeness Issues
Notes for interpretation This event is generated by scanning the pathway from the start of treatment until a gap of 182 days is found. At that point the previous treatment is used as the end of treatment. For single point event treatments (e.g. surgery) the start and end of treatment will co-incide. Death is not taken into account in this event definition, so if treatment is interrupt by death the algorithm will naively take the last recorded treatment in the data as the end of treatment.

Field or property Description
Event name Treatment for recurrence
Event number 606
Date updated 18/06/2025
Linkage Patient
Event definition Treatment for recurrence - must satisfy the following rules: 1. Start with derived end of initial treatment; 2. Look for any active treatment following it, define this to be a recurrence event; 3. No exclusions for second primaries; 4. Do not take hormone or WW/AS as evidence for recurrence.
Property 1 definition Modality code
Property 2 definition N/A
Property 3 definition N/A
Date definition First treatment date after gap.
Trust definition The trust definition is derived from that of the event used.
Data source Derived events are based on existing events in the current AV_PATHWAY build.
Further methodology The events are tumour-linked to the tumour cohort. Event types 7,8,9,10,13,17,18,20,21,22,23,24 are used for this derived event.
DQ/Completeness Issues
Notes for interpretation Experimental field under active development. This scans the pathway from the end of treatment looking for a treatment (after the 182 day gap that event 105 seeks) or other recurrence-signifying event.

Field or property Description
Event name HES Recurrence
Event number 607
Date updated 18/06/2025
Linkage Patient
Event definition Recurrence as recorded by HES.
Property 1 definition The ICD-10 code for the primary diagnosis of the patient in the episode.
Property 2 definition Treatment speciality for the episode as recorded in the TRETSPEF field.
Property 3 definition All ICD-10 diagnostic codes aggregated together in a list, separated by “:”
Date definition The EPISTART field is used to identify the beginning and end of the episode
Trust definition The first three digits of the PROCODE3 field are in the HESAPC field are used.
Data source The HES table is HESLIVE.HESAPC, the diagnosis codes are stored in HESLIVE.HESAPC_DIAG. Data is also drawn from HESLIVE.HESAPC_PROVISIONAL with diagnosis codes in HESLIVE.HESAPC_DIAG_PROVISIONAL.
Further methodology The first episode with a HESAPC diagnositic field (i.e. EVENT_TYPE=4) that includes (‘C77’,‘C78’,‘C79’) is counted as a recurrence. All tumours with a second primary (excluding those in (‘C44’, ‘D40’, ‘D01’, ‘D07’, ‘D03’, ‘D04’, ‘D06’)) are excluded.
DQ/Completeness Issues
Notes for interpretation